98 THE CANNIZZARO REACTION hyde. It has been observed with aldehydes which have a-hydrogei atoms, although generally under conditions quite dissimilar to those employed with aldehydes of the first class. For example, isobutyralde-hyde is reported to undergo quantitative conversion into isobutyric acid and^isobutyl alcohol when heated with barium hydroxide solution at 150° in a sealed tube. 26 There are reports that aldehydes containing two hydrogen atoms on the a-carbon atom undergo the Cannizzaro reaction, 27-28 but the results are inconclusive. In some cases workers unable to repeat earlier experiments 26> 29 attributed the previous results to impurities in the reactants (e.g., methylethylacetaldehyde in isovaler-aldehyde). In another case 28 the extent of the supposed Cannizzaro reaction was deduced only from a decrease in the alkali concentration as the reaction between acetaldehyde and alkali was followed by titration. The •Gannizzaro reaction often occurs indirectly when aldehydes
This is the end of the preview.
access the rest of the document.