DIAZO REACTION 245zene was attempted. Interesting data on the relative merits of variousstabilizing agents and reagents for bringing about coupling with aromaticcompounds may be found in the original paper.6The nitrosoacetyl method usually gives good yields of biaryl com-pounds. It has the disadvantage that oxides of nitrogen must be gener-ated and that unless the nitrosation is carried out carefully the yieldsuffers. A recent innovation employing nitrosyl chloride has eliminatedthe objections of the older nitrosation procedure and promises to be thebest method.Isolation of the Product.The usual method of working up the reac-tion mixtures is to remove the excess of benzene derivative by distillationor steam distillation and then obtain the biaryl by steam distillation bymeans of superheated steam or by keeping the reaction flask in a hot oilbath. This is a tedious process, for continued distillation is necessary
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