Respiratory System Wk8 - Development of the Respiratory...

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Development of the Respiratory System
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During the 4 th week the respiratory diverticulum develops as an outgrowth from the ventral wall of the foregut. Laryngeotracheal groove forms caudal to 4 th pair of pharyngeal pouch Tracheoesophageal ridges form and eventually separate the 2 tubes, esophagus and laryngeotracheal tube
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Larynx The lining is derived from endoderm The cartilage, muscle and connective tissue are derived from splanchnic mesoderm of the 4 th 6 th arch that came from neural crest mesenchyme cells The cranial end mesenchyme produces arytenoid swellings which grow toward the tongue, forming the laryngeal inlet(vocal cords)
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Larynx Rapidly growing epithelia temporarily closes the lumen but this will reopen at about the 10 th week, forming the laryngeal ventricle. This is bounded by the vocal and vestibular folds. The epiglottis develops from the hypobranchial eminence (3 rd th pharyngeal arch) Innervated by vagus nerve The larynx and epiglottis will continue to grow until the third year after birth
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Respiratory System Wk8 - Development of the Respiratory...

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