ANAT 1507 Development of the Skeletal System

ANAT 1507 Development of the Skeletal System - Development...

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Mesodermal (paraxial) Neural Crest Cells Bone and Cartilage Intermembranous bone formation – flat bones develop in mesenchyme within preexisting membraneous sheets Endochondral bone formation – cartilage forms bone Cartilage Mesenchyme condenses – cells become rounded chondroblasts hyaline fibrocartilage elastic Intramembaneous Ossification Mesenchyme surrounded by membrane osteoblasts form matrix and osteoid tissue calcium phosphate is deposited layers around vessels form Haversion systems osteoblasts and osteoclasts form spongy bone Intracartilaginous ossification (Endochondral) Diaphysis (body) epiphysis (ends) Joint Development Begins about week 6 and is adult-like by week 8 Fibrous Cartilagenous (hyaline or fibrous) Synovial – capsule and ligaments – space centrally – membrane that lines the capsule and surfaces Axial Skeleton Skull vertebral column ribs
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ANAT 1507 Development of the Skeletal System - Development...

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