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Unformatted text preview: -need HMG CoA to make 2 AcCoA Acetone Acetoacetate β-Hydroxybutyrate * * *-Nitrogen Metabolism Amino Acid Carbon Skeleton NH 2 glutamate α-KG aspartate OAA H – C – COOH alanine pyruvate R Transamination-enzyme = transaminase / aminotransferase NH 2 NH 2 OAA α-KG OAA α-KG (aspartate) (glutamate) Oxidation Deamination matrix cytoplasm ( glutamate DH) (carbonyl phosphate synthase) NH 2 NH 2 Carbonyl Urea Phosphate a-KG CO 2 ATP Urea Cycle * see large diagram * * *-Ketogenic Amino Acids-Luecine/Lycine # of Rings Precursors End Product Salvaged for ? Purines 2 THF Uric Acid ATP A – G Inosine GTP Pyrimidines 1 Orotic Acid Urea New DNA C – T – U New RNA * * *-HMP Shunt (hexomonophosphate) Glucose NADPH (anti-oxidant) oxidative G6P Ribose F6P non-oxidative...
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- Fall '10
- Fatty acid synthase