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CHEM 1516 Exam 4 Review - Dr Bert Silverman Biochemistry II...

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Dr. Bert Silverman Biochemistry II REVIEW FOR FINAL EXAM LIPID, AMINO ACID & NUCLEIC ACID METABOLISM
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EXAM 42 QUESTIONS 40 = 100% BONUS POINTS Vs EXAM #2 APPROX NUMBER QUESTIONS: LIPID METABOLISM - 16 PROTEIN & AMINO ACIDS - 16 NUCLEIC ACIDS - 10
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KEY WORD REVIEW WHAT FOLLOWS IS A LISTING OF MOST OF THE KEY TERMS FROM YOUR HANDOUTS THE HANDOUTS ARE THE PRIMARY SOURCE MATERIAL FOR YOU AND THEY ARE WHAT I USE TO WRITE YOUR EXAMS LOOK FOR CONTRASTS & COMPARISONS AS AN AIDE FOR LEARNING WHAT DO YOU KNOW; WHAT STORY CAN YOU TELL ABOUT EACH OF THESE TERMS?
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FATTY ACIDS BIOSYNTHESIS DE NOVO BIOSYNTHESIS WHERE ? CYTOPLASM LIVER & WHERE ELSE ? GROW THEM 2C’s AT A TIME acetylCoA ? FATTY ACID SYNTHASE ? MULTIENZYME COMPLEX REQUIRES NADPH (ALSO FOR CHOLESTEROL BIOSYNTHESIS) FROM GLUCOSE ? …..YES = STORED ENERGY, RIGHT ?
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LIPOGENESIS MAKE FAT ! FIRST MAKE FAs FROM GLUCOSE ? INSULIN Vs GLUCAGON ? VERY IMPORTANT ! SEVERE DIABETES ? KETONE BODIES - WHY ?
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BETA OXIDATION OF FA WHY? --->ATP (ABOUT 40% OF OUR ATP) EXCESS GLUCOSE (CALORIES) STORED AS GLYCOGEN AND THAN AS FAT (NEUTRAL TRIGLYCERIDES) HOW? FAT ---> FAs--->acetylCoA --->TCA THEN SOP TO ETC/OXPHOS ---> ATP RBCs ?
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