CHEM 1516 Lactate and Muscle Pain

CHEM 1516 Lactate and Muscle Pain - Lactate Not Guilty as...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Lactate: Not Guilty as Charged Len Kraviz, Ph.D. Study Reviewed: Robergs, R.A., Ghiasvand, F., & Parker, D. (2004). Biochemistry of exercise- induced metabolic acidosis. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 287: R502-R516. Introduction During intense exercise the development of the “burn” in muscle, referred to as acidosis, has been traditionally explained as an increase in the body’s production of lactic acid. This “lactic acid” cause of acidosis, referred to as “lactic acidosis” is taught in many physiology, biochemistry and exercise physiology courses throughout the world. The cause of the acidosis during intense exercise has been a weighty topic of discussion and debate with fitness professionals and personal trainers for years. Many fitness specialists believe that lactic acid or lactate (See Acidosis Question Box #1 for explanation of difference) production is the cause of muscle fatigue during vigorous exercise. Most recently, Robergs and colleagues (2004) have completed an extensive review of the biochemistry of exercise- induced metabolic acidosis. This expansive reexamination details a much more inclusive and enlightening understanding of lactate production and acidosis. From this recent publication, brief highlights of the history of lactic acid understanding will be presented as well as a more contemporary scientific understanding of acidosis. Some meaningful practical training applications for the applied fitness professional will be offered. Lactic Acic: Brief History Robergs et al. (2004) identify the discovery of lactic acid in 1789 to Carl Whilhelm Sheele, a Swedish chemist. Sheele isolated an acid in sour milk samples. This milk origin led to the naming of this acid to ‘lactic’, which means relating to milk. Continuing with their historical account, Robergs et al. note that by 1810 chemists had verified the presence of lactic acid in other organic tissues such as fresh milk, meat and blood. In 1833, the actual chemical formula for lactic acid was determined. By 1869, scientists observed different isomers (atomic compounds with different energy states) of lactic acid along with its formation in fermentation reactions. Fermentation is an enzyme-driven chemical change in an organic (has carbon) compound whereby the substance is split into simpler compounds. Since lactic acid is a naturally occurring molecule, originally detected
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/21/2011 for the course CHEM 1516 taught by Professor Bertsilverman during the Fall '10 term at Life Chiropractic College West.

Page1 / 4

CHEM 1516 Lactate and Muscle Pain - Lactate Not Guilty as...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online