genetics++Fall+_11+stu

genetics++Fall+_11+stu - The The Genetic Revolution: New...

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The Genetic Revolution: New Paradigms for Nutrition and Medical Practice Developed by Gail P. A. Kauwell, PhD, RD, LDN HUN 4446 - Fall2011 1 The Genetic Revolution: New Paradigms for Nutrition and Medical Practice Objectives Appreciate the ethical, legal and social issues related to genomic research; consider the implications for society. Demonstrate an understanding of genetics concepts and nomenclature (i.e., SNP, genotype, phenotype, nutrigenetics nutrigenomics/nutritional genomics nutrigenetics/nutrigenomics/nutritional genomics, epigenetics, methylation, uracil misincorporation, etc.) by correctly applying these terms and concepts to answer questions about situations described in case scenarios. Analyze and interpret data and information that represent examples of nutritional genomic research findings to make predictions about disease risk, outcomes and/or appropriate nutritional recommendations. Outline Human Genome Project Ethical, legal and social issues of genomic research Mini review of genetics Nutritional genomics folate-gene interactions epigenetics
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The Genetic Revolution: New Paradigms for Nutrition and Medical Practice Developed by Gail P. A. Kauwell, PhD, RD, LDN HUN 4446 - Fall2011 2 The Human Genome Project Main Goals : Determine sequence of bases Identify the genes in human DNA Address legal, ethical & social issues The Human Genome Project April 14, 2003 “Finished” human genome sequence April 25 th National DNA Day The Human Genome Project Decoding DNA. .. the biological equivalent of …. . the lunar landing
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The Genetic Revolution: New Paradigms for Nutrition and Medical Practice Developed by Gail P. A. Kauwell, PhD, RD, LDN HUN 4446 - Fall2011 3 The Human Genome Project 1 human = ~2.85 billion base pairs 20 000 25 000 ~20,000-25,000 genes ~2 to 5% of human genome contains genes The Human Genome Project DNA sequence is 99.5% identical The Human Genome Project Improvements in medicine
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The Genetic Revolution: New Paradigms for Nutrition and Medical Practice Developed by Gail P. A. Kauwell, PhD, RD, LDN HUN 4446 - Fall2011 4 The Human Genome Project Designer drugs The Human Genome Project More accurate risk assessment The Human Genome Project Tailored nutrition therapy
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The Genetic Revolution: New Paradigms for Nutrition and Medical Practice Developed by Gail P. A. Kauwell, PhD, RD, LDN HUN 4446 - Fall2011 5 The Human Genome Project Improved nutritional quality of foods Other Research Programs • Single nucleotide polymorphisms (SNPs) • International HapMap Project (haplotype map map) • ENCODE • The Cancer Genome Atlas • Human Epigenomics Project Ethical, Legal and Social Implications Issues : 1) Fairness in use of genetic information 2) Privacy & confidentiality Who has access? How should it be used? Who owns and controls it?
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The Genetic Revolution: New Paradigms for Nutrition and Medical Practice Developed by Gail P. A. Kauwell, PhD, RD, LDN HUN 4446 - Fall2011 6 Ethical, Legal and Social Implications Genetic discrimination : Individuals or family members with genetic problem: • 25% refused life insurance
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This note was uploaded on 11/21/2011 for the course HUN 4446 taught by Professor Mathews during the Fall '09 term at University of Florida.

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genetics++Fall+_11+stu - The The Genetic Revolution: New...

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