intest+Fall+_11+stu

intest+Fall+_11+stu - Diseases/Disorders of the Intestinal...

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Diseases/Disorders of the Intestinal Tract 1 Developed by Gail P. A. Kauwell, PhD, RD, LDN Updated by Gail P. A. Kauwell, PhD, RD, LDN & Anne Mathews, PhD, RD HUN 4446 - Fall 2011 Diseases of the Intestinal Tract • Compare normal gastrointestinal (GI) structure and function to the changes that occur in diseases/disorders of the lower GI tract. • Describe the etiology, symptoms, clinical findings and pathophysiology associated with diseases/disorders of the lower GI tract. Objectives • Describe the diagnostic tests/procedures and intervention strategies (i.e., medical, surgical, pharmacologic, nutritional) used to treat/manage diseases/disorders of the lower GI tract. • Differentiate among diseases/disorders of the lower GI tract based on risk factors, etiology, symptoms, clinical findings, laboratory data, diagnostic tests, pathophysiology and medical/surgical, pharmacological and nutritional management. • Relate the signs, symptoms, clinical findings, laboratory data, diagnostic tests, and medical, surgical, pharmacologic and nutritional interventions to the underlying pathophysiology of diseases/disorders of the lower GI tract. • Interpret the results of laboratory/diagnostic tests Objectives Interpret the results of laboratory/diagnostic tests. • Recommend appropriate nutritional management for patients with diseases/disorders of the lower GI tract based on information presented in case studies. • Select appropriate medical, pharmacologic and/or surgical interventions for patients with diseases/disorders of the lower GI tract based on information presented in case studies.
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Diseases/Disorders of the Intestinal Tract 2 Developed by Gail P. A. Kauwell, PhD, RD, LDN Updated by Gail P. A. Kauwell, PhD, RD, LDN & Anne Mathews, PhD, RD HUN 4446 - Fall 2011 Celiac Disease Celiac disease : • autoimmune disease; an immune-mediated enteropathy Celiac disease gluten-sensitivity • gluten = offending agent Gluten sensitivity : • no immunologic or allergic component • gluten is offending agent Pathogenesis: Factors resulting in autoimmune intestinal enteropathy): Celiac Disease enteropathy): • genetic predisposition • increased intestinal permeability • environmental trigger -ingestion of gluten-containing grains/foods Effects of autoimmune response: • intestinal damage •f lattening & atrophy of intestinal villi Celiac disease • disturbed nutrient absorption & transport • extraintestinal effects
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Diseases/Disorders of the Intestinal Tract 3 Developed by Gail P. A. Kauwell, PhD, RD, LDN Updated by Gail P. A. Kauwell, PhD, RD, LDN & Anne Mathews, PhD, RD HUN 4446 - Fall 2011 Patients with classic GI symptoms only represent the tip of the iceberg Source: The Children’s Digestive Health and Nutrition Foundation, November 2008 (http://www.celiachealth.org).
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intest+Fall+_11+stu - Diseases/Disorders of the Intestinal...

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