LIVER+Fall+_11+stu

LIVER+Fall+_11+stu - Liver Disease Diseases of the Liver...

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Liver Disease 1 Developed by Gail P. A. Kauwell, PhD, RD, LDN Updated by Gail P. A. Kauwell, PhD, RD, LDN & Anne Mathews, PhD, RD HUN 4446 - Fall 2011 Diseases of the Liver Objectives • Compare normal liver structure and function to the changes that occur in diseases/disorders of the liver. • Describe the etiology, symptoms, clinical findings and pathophysiology associated with diseases/disorders of the liver. • Describe the diagnostic tests/procedures and intervention strategies (i.e., medical, surgical, pharmacologic, nutritional) used to treat/manage diseases/disorders of the liver. • Differentiate among diseases/disorders of the liver based on risk factors, etiology, symptoms, clinical findings, laboratory data, diagnostic tests, pathophysiology and medical/surgical, pharmacological and nutritional management. Objectives • Relate the signs, symptoms, clinical findings, laboratory data, diagnostic tests, and medical, surgical, pharmacologic and nutritional interventions to the underlying pathophysiology of diseases/disorders of the liver. • Interpret the results of laboratory/diagnostic tests. • Recommend appropriate nutritional management for patients with diseases/disorders of the liver based on information presented in case studies. • Select appropriate medical, pharmacologic and/or surgical interventions for patients with diseases/disorders of the liver based on information presented in case studies.
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Liver Disease 2 Developed by Gail P. A. Kauwell, PhD, RD, LDN Updated by Gail P. A. Kauwell, PhD, RD, LDN & Anne Mathews, PhD, RD HUN 4446 - Fall 2011 Liver: Structure and Function essential for life General • 2 lobes http://www.fotosearch.com/LIF115/sa402016/ Also, figure on p 439 of text on reserve at Marston Library portal vein Blood supply Liver: Structure and Function hepatic artery sinusoids central hepatic vein inferior vena cava Also see page 440of text Structure Liver: Structure and Function hepatocytes • bile canaliculi See diagram in text on reserve at Marston Science Library (p 439).
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Liver Disease 3 Developed by Gail P. A. Kauwell, PhD, RD, LDN Updated by Gail P. A. Kauwell, PhD, RD, LDN & Anne Mathews, PhD, RD HUN 4446 - Fall 2011 Liver: Structure and Function See figure in text on reserve at Marston Science Library (p. 439). Functions blood volume regulation • detoxification Liver: Structure and Function • bile production • emulsifying agent • important to fat absorption; micelle formation • metabolic functions Bile Synthesis and Enterohepatic Circulation See diagram in text on reserve at Marston Science Library (p 441).
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Liver Disease 4 Developed by Gail P. A. Kauwell, PhD, RD, LDN Updated by Gail P. A. Kauwell, PhD, RD, LDN & Anne Mathews, PhD, RD HUN 4446 - Fall 2011 Examples of metabolic functions CHO metabolism Liver: Structure and Function : • glycogen synthesis & storage • glycogenolysis • monosaccharide conversion • conversion of AA residues Examples of metabolic functions fat metabolism : • formation of lipoproteins Liver: Structure and Function • fatty acid oxidation • cholesterol & phospholipid synthesis
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LIVER+Fall+_11+stu - Liver Disease Diseases of the Liver...

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