HUN 4446 – Fall 2011
Study Guide Questions – Test 1
September 28, 2011
The test will be multiple choice and will include several case studies that require critical
thinking skills. Read the case study carefully before you start to answer the questions.
Please keep in mind that you will need to know the information we discussed in class
well enough so that you can apply the information to different scenarios. You will need to
be able to go beyond recognizing information that we discussed in class in order to do
well on the test.
Nutrition and Genetics/Genomics
Define/know terms: genotype, phenotype, epigenetics, allele, DNA methylation,
uracil misincorporation, single nucleotide polymorphism, heterozygous, homozygous
(normal; variant), etc.
Demonstrate an understanding of genetics concepts and nomenclature (i.e., SNP,
genotype, phenotype, epigenetic, nutrigenetics/nutrigenomics, methylation, uracil
misincorporation, heterozygous, homozygous, etc.) by correctly applying these terms
and concepts to answer questions about situations described in case scenarios or other
situations posed in the questions.
What is the significance of the MTHFR 677C
T single nucleotide polymorphism in
terms of chronic disease risk and NTD risk? What are the implications for nutrition
Analyze and interpret data and information that represent examples of nutritional
genomic research findings to make predictions about disease risk, outcomes and/or
appropriate nutritional recommendations.
What is dysphagia? Odynophagia? Sitophobia?
Differentiate between the categories of dysphagia.
Distinguish among the potential causes of dysphagia (i.e., neurological, motor,
structural/mechanical) and the related signs and symptoms associated with the various
Describe the methods/tests used to assess swallowing function.
Describe the nutritional considerations/management recommended for patients with
different types of dysphagia.
Esophageal Disorders: Achalasia, GERD, etc.
Describe the normal function of the esophagus and the lower esophageal sphincter
What changes occur in esophageal/LES function in patients with achalasia? What is
the underlying problem?
What signs and symptoms occur in association with achalasia? Relate these signs and
symptoms, when possible, to functional changes that occur in this disease process.
How is achalasia diagnosed?