2011kinetoplastids

2011kinetoplastids - Protozoa: Single Celled Organisms...

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Protozoa : » Single Celled Organisms » Eukaryotic Trematodes, Cestodes -Flatworms Nematodes – Roundworms Arthropods Phylum Sarcomastigophora ( have flagella, pseudopodia or both). Subphylum Sarcodina (protoplasmic flow without discrete pseudopodia). Examples: Entamoeba , Naegleria Subphylum Mastigophora (trophozoites are motile stage, typically contain 1 to few flagellar). Examples: Leishmania , Giardia , Trichomonas Phylum Ciliophora ( have simple or compound cilia, two types of nuclei). Example: Balantidium Phylum Apicomplexa (have apical complex – micronemes, conoids…). Examples: Plasmodium , Toxoplasma
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Order Kinetoplastida Subphylum Mastigophora Order Kinetoplastida Family Trypanosomatidae Genus Trypanosoma Subgenus– Schizotrypanum ( Stercoraria -posterior gut development) discontinuous development in mammalian host. Vector is Triatoma (Reduviid bug). Organism - Typanosoma cruzi Subgenus Trypanozoon ( Salivaria - anterior gut development) continuous development in mammalian host. Vector is Glossina (Tsetse fly). Organisms: T. brucei bruce i, T. brucei gambiens e, T. brucei rhodesiens e. Genus Leishmania - Vector is Phlebotomus or Longipalpis (sandfly) General Characteristics • Kinetoplast - specialized mitochondrial structure containing tightly packed DNA in mini and maxi circles • Have a single mitochondrion. • Undulating membrane • Microtubules (subpellicular). • Glycosomes, where carbohydrate metabolism occurs when the mitochondrion is minimally functional.
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Overall Morphology • Forms differ in location of the kinetoplast relative to the nucleus and the single flagellum • Trypomastigote • Epimastigote • Promastigote • Amastigote (intracellular form ) flagellum not exteriorized
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Order Kinetoplastida Subphylum Mastigophora Order Kinetoplastida Family Trypanosomatidae Genus Trypanosoma Subgenus– Schizotrypanum (Stercoraria-posterior gut development) discontinuous development in mammalian host. Vector is Triatoma (Reduviid bug). Organism - Typanosoma cruzi [-amastigote-trypomastigote-epimastigote-metacyclic trypomastigote-trypomastigote-] Subgenus Trypanozoon ( Salivaria - anterior gut development) continuous development in mammalian host. Vector is Glossina (Tsetse fly). Organisms: T. brucei bruce i, T. brucei gambiens e, T. brucei rhodesiens e. [-Trypomastigote (long slender/short stumpy)-procyclic trypomastigote—metacylic trypomastigote-] Morphological forms in the life cycle of kinetoplastids
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Disease) T. cruzi is transmitted by blood sucking triatomine bugs (Reduviid bugs, kissing bug, assassin bug). Rhodnius prolixus, Triatoma infestans • Reduviid bugs - in the wild, nooks and crannies of substandard dwellings. • Species differ in feeding
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This note was uploaded on 11/21/2011 for the course ZOO 4232 taught by Professor Kima during the Fall '10 term at University of Florida.

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2011kinetoplastids - Protozoa: Single Celled Organisms...

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