Practice_Questions_Ch17 - 1 Identify the cytoskeletal...

1 Identify the cytoskeletal structures depicted in the epithelial cells shown in the
figure
2 Which of the following statements about the cytoskeleton is false ?
(a) The cytoskeleton is made up of three types of protein filament.
(b) The bacterial cytoskeleton is important for cell division and DNA
segregation.
(c) Protein monomers that are held together with covalent bonds form
cytoskeletal filaments.
(d) The cytoskeleton of a cell can change in response to the environment.
3 Indicate which of the three major classes of cytoskeletal elements each statement
below refers to.
A. monomer that binds ATP
B. includes keratin and neurofilaments
C. important for formation of the contractile ring during cytokinesis
D. supports and strengthens the nuclear envelope
E. their stability involves a GTP cap
F. used in the eucaryotic flagellum
G. a component of the mitotic spindle
H. can be connected through desmosomes
I. directly involved in muscle contraction
J. abundant in filopodia
4 Which of the following statements about the cytoskeleton is true?
(a) All eucaryotic cells have actin, microtubules, and intermediate filaments
in their cytoplasm.
(b) The cytoskeleton provides a rigid and unchangeable structure important
for the shape of the cell.
(c) The three cytoskeletal filaments perform distinct tasks in the cell and act
completely independently of one another.
(d) Actin filaments and microtubules have an inherent polarity, with a plus
end that grows more quickly than the minus end.
5 Which of the statements below about intermediate filaments is false ?
(a) They can stay intact in cells treated with concentrated salt solutions.
(b) They can be found in the cytoplasm and the nucleus.
(c) They can be anchored to the plasma membrane at cell-cell junction.
(d) Each filament is about 10 μ m in diameter.
(A) (B) (C)

6 For each of the following sentences, fill in the blanks with the best word or phrase
selected from the list below. Not all words or phrases will be used; use each word
or phrase only once.
Intermediate filaments are found mainly in cells that are subject to
mechanical stress. Mutations in genes that disrupt intermediate
filaments cause some rare human diseases. For example, the skin of
people with epidermolysis bullosa simplex is very susceptible to
mechanical injury; people with this disorder have mutations in their
__________________ genes, the intermediate filament found in
epithelial cells. These filaments are usually connected from cell to cell
through junctions called __________________s. The main filaments
found in muscle cells belong to the __________________ family;
people with disruptions in these intermediate filaments can have
muscular dystrophy. In the nervous system, __________________s
help strengthen the extremely long extensions often present in nerve
cell axons; disruptions in these intermediate filaments can lead to
neurodegeneration. People who carry mutations in the gene for
__________________, an important protein for cross-linking
intermediate filaments, have a disease that combines symptoms of
epidermolysis bullosa simplex, muscular dystrophy, and
neurodegeneration.