FromDiabetes Care1999; 22:896–903weight loss between the two groups at thea50.05 level.Excluded dataOne subject in the standard therapygroup had fasting plasma triglycerides atbaseline.2,000 mg/dl, so this value wasexcluded as an outlier from both baselineand 12-month change comparisons. Onesubject from the combination therapygroup was excluded from the linear re-gression estimate because the subject’sweight loss was more than twice as largeas any other subject and would have led toextrapolating the regression line. Thissubject’s weight decreased by 20 kg andued study participation before 1 year. Rea-sons for discontinuation were inability tokeep study visits (two subjects), desire tostart a commercial weight loss program(two subjects), and personal reasons (onesubject). Thus, 54 subjects (92%) com-pleted 12 months of study participation.There were no signiFcant differencesbetween the two treatment groups inbaseline demographic, clinical, or meta-bolic parameters (Table 1). The majority
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