L19handout - PUBH 7430 Lecture 19 J. Wolfson Division of...

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Unformatted text preview: PUBH 7430 Lecture 19 J. Wolfson Division of Biostatistics University of Minnesota School of Public Health November 15, 2011 Random slopes Random effects model for effect of GART on HIV viral load Viral loads within individuals are correlated across time Subjects start study with different viral loads (recall: not randomized study, so start level may be systematically different between groups) Subjects may also have different inherent HIV viral load trajectories across time Y ij = + 1 time ij + 2 trt ij + 3 time ij trt ij + b i + b 1 i time ij + ij...
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L19handout - PUBH 7430 Lecture 19 J. Wolfson Division of...

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