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Unformatted text preview: Visceral Physiology Notes Chapter 25 – Body Fluid Compartments We are made up of a conglomeration of many different systems (each with its own organs and tissues that serve a common function) that are connected with fluids . • The circulatory system connects all these organs/tissues to make the system a whole • ATP is needed by every cell to perform optimally o We get ATP through oxidative phosphorylation of glucose • If the system is provided with adequate oxygen, we are able to extract more energy in a usable form in a biological system. • All of the chemical reactions occur within the cell membrane – doesn’t matter what kind of cell (neuron, muscle cell, etc…) o Oxygen and glucose need to be brought into the cell before they can be utilized Body Fluid Compartments – Extracellular and intracellular Fluids – interstitial fluid and edema • Fluids connect all the systems of the body through the circulatory system • All chemical reactions occur within the cell membrane 60:40:20 Rule – tells you how much water is in the ECF, ICF, and total body • Ratio/percentage (TBW (60%): ICF (40%): ECF (20%)) o TBW – Total Body Water – of the total body weight, 60% is made up of water All material that is going to be used inside the cell to perform a particular function needs to pass through the cell membrane So the total body water can be in two different places (divided by the cell membrane) o ICF – Intracellular Fluid – fluid content within the cell membrane 40% of the total body water is inside the cell membrane o ECF – Extracellular Fluid – fluid content outside of the cell membrane 20% of the total body water is outside the cell membrane • Numbers of normal average water percentage table in Guyton Average adult human being weighs about 70 kg (male or female) – 70 kg = total body weight • How much of this “normal” persons body weight is due to the water content? o Assume – 1 kg of water occupies 1 L o 60% of 70 kg is 42 kg of water – occupies 42 L of total body water o 40% of 70 kg is 28 kg of water – occupies 28 L of total body water o 20% of 70 kg is 14 kg of water – occupies 14 L of total body water o 42L: 28L: 14L • 7% of a person total body weight is equivalent to blood volume o What is the blood volume of the average adult human (70 kg)? 7% of 70 kg is 4.9 L What are the three different cell types found in the blood? • Erythrocytes, leukocytes, thrombocytes (platelets) • 5% of a person total body weight will give a pretty good estimate of plasma volume o Plasma – the liquid portion of the blood without the cellular components (not a formed element of blood) Gender Differences • Female have a little more adipose tissue – stored energy (triglycerides) needed for pregnancy o The higher the lipid content in an individual, the lower the water content This theory fits for comparing two individuals of the same sex (lean vs....
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