This preview shows pages 1–2. Sign up to view the full content.
This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: Nonspecific Defenses, Complement system •Cascade of ~11 plasma complement proteins (C) •Destroy target cell membranes •Stimulate inflammation •Attract phagocytes •Enhance phagocytosis Complement proteins interact with on another via two pathways •Classical •Alternative (Part 5 - Complement System) Nonspecific Defenses, Inflammation •Localized tissue response to injury producing •Swelling •Redness •Heat •Pain •Effects of inflammation include •Temporary repair of injury •Slowing the spread of pathogens •Mobilization of local, regional, and systemic defenses (Part 6 - Inflammatory Response) Nonspecific Defenses, Fever •Maintenance of a body temperature above 37.2 o C (99 o F) •Pyrogens reset the hypothalamic thermostat and raise body temperature •Pathogens, toxins, antigen-antibody complexes can act as pyrogens...
View Full Document