Protein sequence databases

Protein sequence databases - Protein sequence databases The...

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Protein sequence databases The two protein sequence databases SWISS-PROT and PIR are different from the nucleotide databases in that they are both curated . This means that groups of designated curators (scientists) prepare the entries from literature and/or contacts with external experts. SWISS-PROT SWISS-PROT is a protein sequence database which strives to provide a high level of annotations (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. It was started in 1986 by Amos Bairoch in the Department of Medical Biochemistry at the University of Geneva. This database is generally considered one of the best protein sequence databases in terms of the quality of the annotation. Its size is given in the table below. TrEMBL is a computer-annotated supplement of SWISS-PROT that contains all the translations of EMBL nucleotide sequence entries not yet integrated in SWISS-PROT. The procedure that is used to produce it was developed by Rolf Apweiler. The
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Protein sequence databases - Protein sequence databases The...

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