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Unformatted text preview: (a common autosomal recessive disease) have occurred in which one parent was a heterozygous carrier of the disease but the second parent had two wild type alleles. The child had received two copies of the mutant chromosome 7 from the carrier parent and no chromosome 7 from the unaffected parent. linkage When two genes are close together on the same chromosome they tend to be inherited together because of the mechanics of chromosome segregation at meiosis. This means that they do not obey the law of independent assortment. The further apart the genes are the more opportunity there will be for a chiasma to occur between them. When they get so far apart that there is always a chiasma between them then they are inherited independently. The frequency with which the genes are separated at miosis can be measured and is the basis for the construction of genetic linkage maps (of which, more in lectures 8 & 9 )....
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This note was uploaded on 11/22/2011 for the course CHEMISTRY CHM1025 taught by Professor Laurachoudry during the Fall '10 term at Broward College.
- Fall '10