Sensitivity and specificity

Sensitivity and specificity - Sensitivity and specificity...

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Sensitivity and specificity How can we measure how good a pattern is at detecting a particular sequence feature? There are two different, complementary measures that can be used to describe how well a pattern performs: Sensitivity is the fraction of the true matches that actually are correctly predicted as matches by the pattern. If the pattern is too stringent (to avoid garbage), then too few of the true matches will be identified by it. Specificity is the fraction of the sequences predicted as matches that really are true matches. If the pattern is too inclusive (to catch as many as possible), then a lot of garbage will also be falsely identified by it. We want a pattern to be both sensitive and specific, so that all true matches are found, and nothing but true matches. But as usual, nature will rarely allow us to find such a pattern; we must try to find a good compromise. A regular expression can easily be designed that has 100% sensitivity: just use the expression that matches anything:
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This note was uploaded on 11/22/2011 for the course CHEMISTRY CHM1025 taught by Professor Laurachoudry during the Fall '10 term at Broward College.

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Sensitivity and specificity - Sensitivity and specificity...

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