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Unformatted text preview: Angelman syndrome and Prader-Willi syndrome are two different conditions both of which seem to be caused by very similar deletions of a small part of chromosome 15. In this diagram, two genes are shown in the critical region. Each is inactivated by imprinting , the Angelman syndrome gene is turned off on the chromosome inherited from the father while the Prader-Willi gene is turned off on the maternally transmitted chromosome. When a deletion covering the region is inherited on the other chromosome one syndrome or the other results. Recommended reading The topics include: • sex determination • sex chromosomes • sexual identity • sex linkage • X inactivation • sex limited and sex influenced traits • imprinting...
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- Fall '10
- Chemistry, Angelmansyndrome