structural aberrations - structural aberrations From time...

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structural aberrations From time to time a cell sustains damage from for instance an energetic cosmic ray particle passing through and leaving behind a trail of ionisation. This may lead to chromosome breakage. The repair systems in the nucleus will do their best to make good the damage and if this involves only one break they may be able to do so with no errors. However, if more than one break has occured they may become rejoined in the wrong combinations. This can lead to one of a spectrum of possibilities. balanced rearrangements Rearrangements where there is no visible loss or gain of genetic material are balanced . They include: inversions, peri- and para-centric In an inversion, a piece of chromosome is lifted out, turned arround and reinserted. If this includes the centromere then the inversion is termed pericentric . If it excludes the centromere then it is a paracentric inversion. The two have slightly different genetic consequences.
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structural aberrations - structural aberrations From time...

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