The linkage map - The linkage map Because genes are...

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The linkage map Because genes are organized along a linear structure, a DNA molecule, we could expect to create a linear map if we measure the frequencies of recombination between them. We make the recombination frequency the measure of the genetic distance between loci. The map unit corresponds to 1% recombination and is named a centiMorgan in honour of Thomas Hunt Morgan. So the purple and vestigial genes above are 10.7cM apart. SAQ 1. Here is a table of recombination frequencies for pairs of X linked genes in Drosophila. Use the information to construct a map of the chromosome. gene 1 gene 2 recombination frequency yellow white 0.010 yellow vermilion 0.322 white vermilion 0.297 vermilion miniature 0.030 white miniature 0.337 white rudimentary 0.452 vermilion rudimentary 0.269 Answer Three point crosses The data in the question above come from seven separate crosses each involving only two genes. If a cross is set up involving more than one pair of genes it can confirm the approximately linear nature of the map and, by consideration of the relative
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This note was uploaded on 11/22/2011 for the course CHEMISTRY CHM1025 taught by Professor Laurachoudry during the Fall '10 term at Broward College.

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The linkage map - The linkage map Because genes are...

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