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Unformatted text preview: distances between them. There are some differences, The gene ABO is not resolved from marker locus D9S150 on the genetic map whereas, in physical reality there is a good sized gap. Differences like this occur because the rate of genetic recombination is not absolutely even throughout the genome, some areas are hot spots and others are areas of reduced recombination. This is reflected in the genetic distances between pairs of markers. The total genetic map length of the human genome is about 3,000 cM and by a lucky coincidence, the total genome length is about 3,000 million basepairs. So on average, 1 cM is equivalent to 1 Mb (Mb = million basepairs). In this region of chromosome 9 there is an elevated recombination rate compared to the genome average and so here 1 cM = ~ 300 kb....
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This note was uploaded on 11/22/2011 for the course CHEMISTRY CHM1025 taught by Professor Laurachoudry during the Fall '10 term at Broward College.
- Fall '10