The Polymerase Chain Reaction

The Polymerase Chain Reaction - The Polymerase Chain...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
The Polymerase Chain Reaction This invention has revolutionised molecular genetics by doing away with the need to clone DNA in many circumstances where it used to be necessary. It is so poweful that it has made it possible to produce microgram amounts (that's a lot!) of DNA starting from just a single molecule. This has applications in forensic science, in archeology (Neandertal mitochondrial DNA amplified from ancient bones by PCR was recently sequenced), and in medicine where, for example, it can enable antenatal DNA tests to be performed in just a few hours work and large populations can be screened for particular mutations very quickly and cheaply.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
DNA sequencing At the heart of the so called "new genetics" is our ability to sequence DNA rapidly and cheaply. With knowledge of sequence comes knowledge of gene structure and very often a beginning of understanding of gene function. The simplest method of sequencing DNA was invented by Dr. Fred Sanger for which he was awarded his second Nobel Prize. In the UK our major national Human Genome Project DNA
Background image of page 2
sequencing centre is named after him, the Sanger Centre in Cambridgeshire. You can
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/22/2011 for the course CHEMISTRY CHM1025 taught by Professor Laurachoudry during the Fall '10 term at Broward College.

Page1 / 4

The Polymerase Chain Reaction - The Polymerase Chain...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online