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Genetics2 - Year 12 Biology Year Module 3 The Species...

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Year 12 Biology Year 12 Biology Module 3: The Species Outcomes covered: 3.8, 3.9, 3.10, 3.11
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Autosomal Dominant Autosomal Dominant Inheritance Inheritance Dominant gene located on 1 of the autosomes Letters used are upper case ie BB or Bb Affected individuals have to carry at least 1 dominant gene (heterozygous or homozygous) Passed onto males and females Every person affected must have at least 1 parent with the trait Does not skip generations E.g. Huntington’s disease, Marfan syndrome
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Autosomal Dominant- Marfan Autosomal Dominant- Marfan syndrome syndrome
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Autosomal Recessive Autosomal Recessive Inheritance Inheritance The recessive gene is located on 1 of the autosomes Letters used are lower case ie bb Unaffected parents (heterozygous) can produce affected offspring (if they get both recessive genes ie homozygous) Inherited by both males and females Can skip generations If both parents have the trait then all offspring will also have the trait. The parents are both homozygous. E.g. cystic fibrosis, sickle cell anaemia, thalassemia
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Autosomal Dominant/ Autosomal Dominant/ Recessive Problems Recessive Problems Cross a pure breeding, black coated guinea pig with a pure breeding, white coated guinea pig. Given that, in guinea pigs, black coat colour is dominant to white coat colour, determine the genotypes and phenotypes of the first and second generation offspring.
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Incomplete dominance Incomplete dominance In a heterozygous organism, neither gene is dominant, both genes are expressed equally Capital letters used for both alleles Snap dragons- red = RR, white= WW, pink = RW Cows- brown = BB, white= WW, roan=BW
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Incomplete dominance Incomplete dominance
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