gene function and structure

gene function and structure - What is a gene? Definitions...

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What is a gene?
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Definitions of the gene The gene is to genetics what the atom is to chemistry. The gene is the unit of genetic information that controls a specific aspect of the phenotype. The gene is the unit of genetic information that specifies the synthesis of one polypeptide.
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How has the concept of a gene developed in the minds of geneticists?
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Mendel (1866) Inheritance is governed by “characters” or “constant factors” that each controls a phenotypic trait such as flower colour.
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Garrod (1909) Inborn errors of Metabolism Inherited human metabolic disorders such as alkaptonuria result from alternative metabolism. Individual genes can mutate to cause a specific metabolic block. Concept later elaborated as “one gene-one enzyme”. Over 4,000 inherited genetic disorders have now been described.
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Metabolic mutations in Drosophila (Beadle and Ephrussi) Fly eyes are normally dark red because of two pigments, one bright red and one brown. Mutants in
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gene function and structure - What is a gene? Definitions...

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