Thalidomide

Thalidomide - Why did this happen • Simple the drug was not trialled or tested for this use on pregnant women Thalidomide today • Initially the

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Thalidomide
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Thalidomide – the sleeping pill
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Thalidomide was first synthesized in West  Germany in 1953 by Chemie Grünenthal . It was hailed as a  "wonder drug"  that  provided a  "safe, sound sleep".  
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However the drug was also found to cure morning sickness in pregnant women
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Nausea vomiting in pregnancy NVP – 1 st trimester . ..(1/3)
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Foetal development - The first few weeks are a key period – any problems now will accumulate in the future
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Nausea vomiting in pregnancy NVP – 1 st trimester (1/3) When do you think most women would be inclined to take this drug?
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Side effects unfortunately molecules of the thalidomide chemical crossed the placenta and disrupt the growth patterns of the growing foetus
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Effect = catastrophic deformations of the baby– best seen as limb abnormalities.
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…if this was you – how would your life be different?
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Unformatted text preview: Why did this happen? • Simple - the drug was not trialled or tested for this use on pregnant women Thalidomide today • Initially the drug was banned internationally for the treatment of morning sickness • But it has now been reintroduced as a treatment for leprosy Leprosy – bacterial infection of the skin and nerves endings • Affects the hands, feet and features of the face. Leprosy Make key notes on what we have discussed on this drug • Initial use • What it discovered to help • Side effects of untested use • What is it now used for This powerpoint was kindly donated to www.worldofteaching.com http://www.worldofteaching.com is home to over a thousand powerpoints submitted by teachers. This is a completely free site and requires no registration. Please visit and I hope it will help in your teaching....
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This note was uploaded on 11/23/2011 for the course BIO 100 taught by Professor Robinson during the Fall '08 term at BYU.

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Thalidomide - Why did this happen • Simple the drug was not trialled or tested for this use on pregnant women Thalidomide today • Initially the

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