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113lecture1906slides - Microbiology Viruses Viruses and...

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Microbiology - Viruses Viruses and Cancer Latent Viral Infection Prions Oncogenesis Cancers develop when cells are released from normal control on their division – This may also involve release from the tissue in which the transformed cells arose, leading to metastasis – Cancers usually arise from mutation of proto- oncogenes , which encode regulatory proteins • Viral infection may increase the risk of malignant transformation if – Viral gene products influence mutation frequency in host cells – Viral genomes disrupt critical host genes Human Viruses and Cancer • No human virus causes cancer in more than a small minority of infected persons • Nevertheless, viral infection is the second leading known cause of human cancers • Human oncogenic viruses belong to several different families • A common feature is integration of the viral genome into the host cell genome at some point in viral multiplication
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Human Papillomavirus (HPV) • Papovavirus family
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This note was uploaded on 11/24/2011 for the course BIO 113 taught by Professor Staff during the Fall '09 term at Rutgers.

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113lecture1906slides - Microbiology Viruses Viruses and...

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