113lecture2106 - BIOLOGY 113 - MICROBIOLOGY Lecture 21:...

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BIOLOGY 113 - MICROBIOLOGY Lecture 21: Epidemiology - Spread of infection, chain of transmission, patterns of infection Infectious diseases follow a characteristic sequence of events - Predisposing factors influence host susceptibility = Malnutrition is a major factor in susceptibility to a wide variety of infectious diseases, including tuberculosis = Gender, age, lifestyle and genetic factors may also help to determine susceptibility to infection = Interestingly, resistance to infection may vary with "state of mind", the basis for the discipline of psychoneuroimmunology (one of my favorite words!) - Once a pathogen has overcome host resistance, an infectious disease typically follows a pattern characteristic of the disease, including periods of incubation, illness, decline and convalescence (Tortora et al. Figure 14.5) = The incubation period is the period between infection and the appearance of first signs and symptoms = During the prodromal period, mild symptoms may appear, but these are usually not specific to a particular infection = The period of illness is when acute signs and symptoms of the infectious disease occur = The period of decline indicates that the body’s defenses have begun to contain the infection = During the period of convalescence, the body clears the infection (except in persistent or latent infection) and returns to its previous state of resistance For an infectious disease to perpetuate itself, it must have a reservoir of infection that provides the pathogenic microorganism with adequate conditions for survival and multiplication and an
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This note was uploaded on 11/24/2011 for the course BIO 113 taught by Professor Staff during the Fall '09 term at Rutgers.

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113lecture2106 - BIOLOGY 113 - MICROBIOLOGY Lecture 21:...

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