113lecture3706slides - Escherichia coli Proteus spp –...

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Microbial Diseases of the Urinary and Reproductive Systems Human urinary system • Physiological defenses Mechanical flushing Acidic pH Phagocytic cells – Secretory immunoglobulin The urinary tract has not normal microbiota, but the distal urethra is typically colonized by skin flora Human reproductive organs Vagina has a normal microbiota, typically dominated by lactic acid bacteria Eight-fold gender difference in susceptibility to cystitis accounted for by Length of the urethra Proximity to the anus
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Urinary Tract Infection (UTI) Very common bacterial infection • Agents – Gram-negative enterics:
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Unformatted text preview: Escherichia coli , Proteus spp. – Staphylococcus saprophyticus • Cystitis : Inflammation of the bladder • Pyelonephritis : Inflammation of the kidneys – Can lead to kidney damage – Potentially life-threatening • UTI may be asymptomatic Bacterial STDs - Gonorrhea • Neisseria gonorrheae difficult to culture • May be asymptomatic in women, risk for pelvic inflammatory disease • Drug resistance has become a serious problem • Ophthalmia neonatorum is controlled by treating neonates with topical antibiotics U.S. incidence of gonorrhea U.S. distribution of gonorrhea...
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