lecture 30 - tetanus Diphtheria toxin Protein synthesis...

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Mechansims of virulence - adhesion - colonization/invasion Growth Growth colonization  exotixins: Botulism Tetanus disease
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Gran + Types of pathogens: - opportunistic immunocompromised host - Accidental  accidentally introudced ex: wound - Obligate  only replicate within host – virus and bacteria
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Colonize specific tissues – tissue tropism Spread throughout body - bloodstream Aka pertussis
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Does of cells kills 50% of population Few cells More cells
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enzymes Exported into medum botulism
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Unformatted text preview: tetanus Diphtheria toxin Protein synthesis stops = cell death anaerobe Nerves interact with muscles No transmitter Muscle relaxed Laccid paralysis Inhibitory neurons No inhibition muscle contracts Lumen= inside tube Large fluid loss. Not a protein Found in gram (-) bacteria cell walls Increase body temp. LPS Takes amoebocytes from blood extremely sensitive to endotoxins. In the presence of endotoxins the amoebocytes lyse. Measure lysis in clinical lab test...
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lecture 30 - tetanus Diphtheria toxin Protein synthesis...

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