lecture 6 gametogenesis

lecture 6 gametogenesis - Gametogenesis Germ Cell...

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1 Gametogenesis Germ Cell Development Determination Migration Maturation Male germ cell undergoes spermatogenesis Female germ cell undergoes oogenesis Animal Model Examples: Amphibian, Mammal and Insect
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2 Germ Cell Determination Nematodes Insects
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3 Determination: cytoplasmic localization of germ cell determinants (germ plasm ) containing Nanos and Vasa homologuous proteins Migration: The Primordial germ cells do not originate in the developing gonads and must migrate there along directionally oriented paths of fibronectin Maturation: The production of mature haploid gametes; a motile sperm by the process of spermatogenesis and a yolk rich egg by the processes of oogenesis and vitellogenesis. Amphibian Germ Cells
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4 Cytoplamic localization of maternal genes occur Animal to Vegetal in frog oocytes
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5 Determination and Migration of Germ Cells in Xenopus
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6 Hormonal Control of Yolk Production
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7 (A) Hepatocytes prior to estrogen injection. (B) After estrogen injection, hepatocytes expansion for production and secretion of vitellogenin.  (From Skipper and Hamilton, 1977) Effects of estrogen (estradiol) on the ultrastructure of Xenopus laevis liver cells
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8 Growth of Oocytes in the Frog
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9 Schematic Representation of Xenopus oocyte Maturation regulated by MPF
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10 Relative Rates of DNA and RNA synthesis during Xenopus oogenesis
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Looping out at sites of active transcription of DNA into RNA
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lecture 6 gametogenesis - Gametogenesis Germ Cell...

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