Group 4 Wiki Project

Group 4 Wiki Project - DiGeorge syndrome may have several...

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Group 4 Wiki Project: Making a wiki page on the neural crest and DiGeorge Syndrome Background info: The neural crest contains four regions that later develop into different cells and organs. These regions consist of cranial neural crest, cardiac neural crest, trunk neural crest, and vagal and sacral neural crest. There are several conditions that are related to genes on chromosome 22 that lead to defects that are affected by the neural crest cells. These defects in Waardenburg syndrome type I, Treacher Collins syndrome, cleft and craniofacial reconstruction, and DiGeorge syndrome. The defect that we will be focusing on is DiGeorge syndrome. DiGeorge syndrome is characterized as a immunodeficiency disease that is caused by abnormalities of neural crest cells that have migrated into the pharyngeal arches. Patients with
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Unformatted text preview: DiGeorge syndrome may have several abnormalities of the faces such as low set ears and a small mouth; parathyroid gland abnormalities; heart defects; thymus gland abnormalities; and developmental abnormalities such as cleft palate, delayed speech, and/or difficulty in feeding or swallowing. Project Summary: This project will help me better understand how neural crest cells develop and form other cells and organs. It will also help me to understand how DiGeorge syndrome can affect an individual. References: Developmental Biology Textbook, 9 th Edition Part of project I am responsible for is the treatments for DiGeorge syndrome and a case study dealing with DiGeorge Syndrome...
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