Neural Crest Defects

Neural Crest Defects - epinephrine-producing cells of the...

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Neural Crest Defects Courtney Boyd Eric Land Meredith Craver
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The Development and  Migration of Neural Crest  Cells Neural Crest Cells arise  during the process of  Neuralation
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Neural crest cells originating at different  points along the anterior-posterior axis  migrate differently.
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Cranial Neural Crest Cardiac Neural Crest Trunk Neural Crest Vagal and Sacral  Neural Crest Five Regions
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Migrate to the face and pharyngeal arches These cell populations give rise to: Facial bones Connective tissues Cartilage Nerves Odondoblast Schwann cells Cranial Neural Crest
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Migrate to the presumptive heart to form: Aortic septum – dividing the aorta and pulmonary  arteries. Smooth muscle in the aorta and pulmonary arteries Cardiac Neural Crest
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Divide into two groups: Cells that migrate dorsolaterally populate the skin and  give rise to pigment cells. Cells that migrate ventrolaterally give rise to the 
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Unformatted text preview: epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system Trunk Neural Crest Develop into the parasympathetic ganglia Vagal and Sacral Neural Crest Waardenburg Syndrome Type I Treacher Collins Syndrome Cleft and Craniofacial Reconstruction Different Types of Neural Crest Defects Most common type Broad nasal root Patch of white hair or premature gray hair starting at age 12 20% of individuals with WS have hearing impairments Waardenburg Syndrome Type I Outer part of ear appears abnormal or missing Hearing loss Micrognathia (small jaw) Large mouth Coloboma (defect in lower eyelid) Scalp hair reaches to cheeks Cleft palate Treacher Collins Syndrome Cleft and Craniofacial Reconstruction...
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This note was uploaded on 11/26/2011 for the course BIO 361 taught by Professor Dr.bjgrubb during the Fall '10 term at N.C. A&T.

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Neural Crest Defects - epinephrine-producing cells of the...

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