Focus on anthrax - Focus on anthrax Recent events have...

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Focus on anthrax Recent events have confirmed that bioterrorism is no longer a threat but a reality. To provide wide-ranging access to the latest scientific information about anthrax and other potential bioweapons, Nature has put together a special online focus on this issue. This focus is made up of two research papers on anthrax toxin, as well as a collection of research, news and feature articles from our electronic archive. The causative agent of the anthrax disease, the bacterium Bacillus anthracis , secretes a toxin made up of three proteins: protective antigen (PA), oedema factor (OF) and lethal factor (LF). PA binds to cell-surface receptors on the host's cell membranes. After being cleaved by a protease, PA binds to the two toxic enzymes, OF and LA, and mediates their transportation into the cytosol where they exert their pathogenic effects. In addition to these Nature papers, this special focus also includes research from October's issue of Nature Biotechnology . Mourez et al . describe the isolation of a synthetic peptide that blocks the action of anthrax toxin in an animal model. These research papers are complimented by a news feature which looks at the threat of bioterrorism and researchers' attempts to counter it, and a collection of research, news and opinion articles from our archive. Nature 's news and science-writing teams will continue to inform and explain the science behind current events as and when it happens, and this page will be updated accordingly. Featured articles
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Focus on anthrax - Focus on anthrax Recent events have...

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