folicacid

folicacid - TETRAHYDROFOLATE ONE-CARBON REACTIONS H2 N N 1...

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Unformatted text preview: TETRAHYDROFOLATE ONE-CARBON REACTIONS H2 N N 1 N 8a 8 2 H N 3 4 7 6 5 4a 9 N CH2 O H - O N C 10 COO N O CH H H2 N H N O 1 -7 2 NADPH/H 2 NADP H folate - CH2 CH2 C + + H N H H N N O CH2 H - O N C H COO N CH tetrahydrofolate O - CH2 CH2 C H O 1-7 methionine HCOOH homocysteine ADP H H2 N N H2 N H N H N O CH2 CH3 N R N NADPH/H CH2 H O N R HC serine NADP H H N H H N H O N5-methyl THF + synthesis of purine bases Pi H H N N H ATP + N10-formyl THF H2 O glycine H H2 N H N N H H H dTMP H2 N H N N O CH2 CH2 N 10 N5,N -methylene THF R NADP + NADPH/H + H N N H H H N N O HC CH2 N 10 N5,N -methenyl THF R ...
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This note was uploaded on 11/27/2011 for the course CHM 365 taught by Professor Thomaszamis during the Spring '06 term at FSU.

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