lec12 (1) - MIT OpenCourseWare http/ocw.mit.edu 7.88J...

Info icon This preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
MIT OpenCourseWare http://ocw.mit.edu 7.88J Protein Folding Problem Fall 2007 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms .
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Collagen 7.88J Protein Folding Prof. David Gossard October 20, 2003
Image of page 2
PDB Acknowledgements The Protein Data Bank (PDB - http://www.pdb.org/ ) is the single worldwide repository for the processing and distribution of 3-D biological macromolecular structure data. Berman, H. M., J. Westbrook, Z. Feng, G.Gilliland, T. N.Bhat, H.Weissig, I. N.Shindyalov, and P. E.Bourne. “The Protein Data Bank.” Nucleic Acids Research 28 (2000): 235-242. (PDB Advisory Notice on using materials available in the archive: http://www.pdb.org/pdb/static.do?p=general_information/about_ pdb/pdb_advisory.html ) PDB molecules and citations used in the “Collagen” Lecture Notes for 7.88J - Protein Folding PDB ID: 1CGD JRNL reference: Bella, J., M. Eaton, B. Brodsky, and H. M. Berman. “Crystal and molecular structure of a collagen-like peptide at 1.9A resolution.” Science 266 (October 7, 1994):75-8. Pages: 16-17 (“Solved Structure – 1CGD”)
Image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Collagen ~20% of all proteins in human body are collagen Extracellular matrix protein family At least 21 different types of collagen Structural protein Bone, tendon, cartilage, cornea, etc. Mutations in collagen responsible for Osteogenesis imperfecta Hereditary aortic aneurysm
Image of page 4