outline_sg_v - Massachusetts Institute of Technology 5.13:...

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Massachusetts Institute of Technology 5.13: Organic Chemistry II Fall 2003 Outline & Study Guide for Unit V. Carboxylic Acids & Derivatives Penicillin: The Wonder Drug In the late 1800s, Louis Pasteur proposed the ground-breaking hypothesis that diseases were caused by microorganisms. This theory prompted numerous scientists to begin the search for substances that could kill the microorganisms causing the disease without also killing the patient. In the late 1920s, at St. Mary’s Hospital in London, Alexander Fleming found that his bacterial culture plates were contaminated with an airborne fungus. More importantly, he noticed that the fungus inhibited the growth of bacteria on the plate. The fungus was Penicillium notatum , and Fleming named the extract of the fungus penicillin. By the late 1930s, enough penicillin had been extracted to perform successful clinical trials with humans, but British scientists were unable to generate useful amounts of the drug. With World War II raging in Europe, the scientists turned to the United States for assistance.
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This note was uploaded on 11/27/2011 for the course CHEMICAL E 20.410j taught by Professor Rogerd.kamm during the Spring '03 term at MIT.

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outline_sg_v - Massachusetts Institute of Technology 5.13:...

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