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Unformatted text preview: Relative Rate O KOAc, AcOH OAc 7 x 10 7 OSO 2 Ar O H H KOAc, AcOH 1 H OAc O O OSO 2 Ar H b) Please provide a mechanism to account for the formation of the products illustrated below. In addition, explain why no other stereoisomers are generated in the reaction. KOAc, AcOH OSO 2 Ar OAc AcO O O O D D D H 5. Please provide a detailed mechanism for the illustrated transformation. NH 2 HO HO HO HO NH Me H + MeCHO 6. In the reaction illustrated below, the desired product from a simple FriedelCrafts acylation ( A ) was not observed. Instead, and isomeric product ( B ) was generated through a more complex route that also involves FriedelCrafts chemistry. Please provide a detailed mechanism for this unexpected process. CO 2 H OMe O OMe Me OMe O OMe Me OMe O O O Me HF OMe OMe OMe OMe A B desired not desired not observed observed...
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This note was uploaded on 11/27/2011 for the course CHEMICAL E 20.410j taught by Professor Rogerd.kamm during the Spring '03 term at MIT.
- Spring '03
- Organic chemistry