5_60_lecture35

5_60_lecture35 - MIT OpenCourseWare http/ocw.mit.edu 5.60...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
MIT OpenCourseWare http://ocw.mit.edu 5.60 Thermodynamics & Kinetics Spring 2008 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms .
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
1 5.60 spring 2008 Lecture #35 Enzyme Catalysis Readings: SAB, pp. 745-752 Enzymes are biological catalysts, consisting of proteins, that greatly accelerate reaction rates and do so with exquisite specificity . That is, a chemical reaction involving one reactant goes much faster, but other chemical reactions involving the same reactant or the same chemical reaction performed on an analogous reactant are sometimes largely unaffected. ⎯→ S A E P A (accelerated) (not accelerated) P C S B P B (not accelerated) The reactant in an enzymatic process is called a substrate. Examples: invertase 1) Sucrose + H 2 O(C 12 H 22 O 11 ) ⎯⎯⎯→ glucose (C 6 H 12 O 6 ) + f r u c t o s e ( C 6 H 12 O 6 ). OH O HO lactase 2)
Background image of page 2
2 5.60 spring 2008 Lecture #35 3) H COO H H C COO C C + H 2 O fumarase ⎯⎯⎯⎯→ C H OOC H OOC fumarate OH L-malate Key features: rate accelerated product specificity substrate selectivity [invertase does not work on
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 6

5_60_lecture35 - MIT OpenCourseWare http/ocw.mit.edu 5.60...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online