Lecture8HormonesFinalStudy

Lecture8HormonesFinalStudy - Feedback relating to recent...

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Integrative Physiology of Obesity
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Some inbred strain characteristics
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Mouse weighed down by genetics
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Lethal Yellow
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Integrative obesity
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Brainstem
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Lateral Hypothalamus
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VMN
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Hypothalamus
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PVN
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Arcuate
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Endocannabinoids
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POMC
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Gut endocrine hormones
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Hormones from the gut and endocrine organs in food intake Hormonal signals derived from the gut and classical endocrine organs act in synergy to affect changes in feeding behavior. Hormonal signals derived from the gut and classical endocrine organs like the pancreas, thyroid and adrenal glands act in synergy to effect changes in feeding behaviour. CCK, cholecystokinin; OXM, oxyntomodulin; GLP-1, glucagon-like peptide 1; PYY3-36, peptide YY 3-36.
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Gut peptides and the brain
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The brain integrates long-term energy balance. Peripheral signals relating to long-term energy stores are produced by adipose tissue (leptin) and the pancreas (insulin).
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Unformatted text preview: Feedback relating to recent nutritional state takes the form of absorbed nutrients, neuronal signals, and gut peptides. Neuronal pathways relate information about stomach distention and chemical and hormonal milieu in the upper small bowel to the nucleus tractus solitarius (NTS) within the dorsal vagal complex (DVC). D. B. West, D. Fey and S. C. Woods Am J Physiol Regulatory Integrative Comp Physiol 246:776-787, 1984. Or, why isnt CCK used to treat obesity? Cholecystokinin persistently suppresses meal size but not food intake in free-feeding rats CCK meal size Meal duration Daily food intake Meal number Body Weight Insulin and glucose Glucose tolerance test Glycemic index A ranking of carbohydrate-containing foods, based on the food's effect on blood sugar compared with a standard reference food's effect....
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This note was uploaded on 11/24/2011 for the course NPB 97952 taught by Professor ? during the Spring '09 term at UC Davis.

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Lecture8HormonesFinalStudy - Feedback relating to recent...

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