Lecture7BalanceGenetics

Lecture7BalanceGenetics - Energy balance CHANGES IN ENERGY...

Info iconThis preview shows pages 1–14. Sign up to view the full content.

View Full Document Right Arrow Icon
Energy balance
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
CHANGES IN ENERGY EXPENDITURE RESULTING FROM ALTERED BODY WEIGHT Leibel et al New England Journal of Medicine 1995;332:621-8
Background image of page 2
Methods We repeatedly measured 24-hour total energy expenditure, resting and nonresting energy expenditure, and the thermic effect of feeding in 18 obese subjects and 23 subjects who had never been obese. The subjects were studied at their usual body weight and after losing 10 to 20 percent of their body weight by underfeeding or gaining 10 percent by overfeeding.
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Study design
Background image of page 4
Study Diet The subjects were admitted to the Clinical Research Center at Rockefeller University and fed a liquid formula (40 percent fat [corn oil], 45 percent carbohydrate [glucose polymer], and 15 percent protein [casein hydrolysate]) supplemented with 5.0 g of iodized sodium chloride, 1.9 g of potassium ions as a potassium salt, and 2.5 g of calcium carbonate per day, 1 mg of folic acid twice weekly, and 36 mg of ferrous iron every other day.
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Methods Body composition was measured by using hydrodensitometry. Total EE for 24 h (TEE) was assessed on the basis of precise titration of fed calories of a liquid formula diet necessary to maintain body weight with a variance of 10 g/d over14 d.
Background image of page 6
Characteristics and Body Composition of Subjects at Initial and Altered Weights.
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Total EE and weight gain
Background image of page 8
Energy expenditure vs fat free mass
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
24-hour total energy expenditure
Background image of page 10
REE weight loss
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
24 hour resting
Background image of page 12
Non-resting energy Since no technique is available for the direct measurement of non-resting energy expenditure, this component of energy expenditure was calculated as the difference between total energy expenditure and the sum of the resting components of
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 14
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 32

Lecture7BalanceGenetics - Energy balance CHANGES IN ENERGY...

This preview shows document pages 1 - 14. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online