09082011FNTR342-ProtDigest

09082011FNTR342-ProtDigest - Digestion, Absorption, and...

Info iconThis preview shows pages 1–13. Sign up to view the full content.

View Full Document Right Arrow Icon
Digestion, Absorption, and Properties of Proteins Gropper, 4 th ed, Ch 7, pp. 172–185; Ch 2, pp. 31–40, pp. 45–46 Gropper, 5 th ed, Ch 6, pp. 179–194; Ch 2 pp. 56–57
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 Objectives for today: Review chemical structures of proteins and amino acids Review sites of digestion and mechanisms of protein absorption Understand hormonal regulation of the digestive process
Background image of page 2
3 Protein Intro Molecular structure and activity of living cells dependent upon protein Ubiquitous expression: 40% skeletal muscle 25% organs Skin and blood Amino acids constitute body proteins and N- containing molecules
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
4 Animal products: meat, poultry, fish, and dairy (except butter, sour cream, cream cheese) Plant products: grains (and grain products), legumes, and vegetables Endogenous proteins: secreted digestive enzymes and glycoproteins (17 g/day) and shed mucosal cells (50 g/day) Protein Intro
Background image of page 4
5 Functional Categories Enzymes: catalysts Hydrolase, isomerase, ligase, oxidoreductase, transferase Structural proteins: contractile, fibrous, globular Hormones: chemical messengers Steroid, amino acid, or polypeptide chains Immunoproteins: immunoglobulins IgG, IgA, IgM, IgE and IgD
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6 Functional Categories Transport proteins: carriers for vitamins, mineral, and nutrients Cell membranes: uniporters, symporters, antiporters Blood: albumin and lipoprotein pH buffers: amino acids stabilize changes in pH Intracellularly: hemoglobin, amino acids, phosphates Blood: proteins and bicarbonate Fluid balancers: osmotic balance albumin
Background image of page 6
7 Functional Categories Cell-cell adhesion Protein Receptors Conjugated Proteins: Glycoproteins: mucus, connective tissue and hormones Proteoglycans: extracellular matrix Lipoproteins: blood-based carriers of lipids Flavoproteins: enzymes bound to FAD or FMN coenzyme Metalloproteins: storage of minerals-Cu, Fe or Zn
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
8 Amino Acid Classification Structural Net charge Polarity Essentiality
Background image of page 8
9 Amino Acid Structure Central carbon ( α carbon) Amino group (-NH 2 )-accept or donate H+ Carboxyl group (-COOH)-accept or donate H+ Unique side chain (R)-determine structure and chemical characteristics α H 2 N-CH-COOH | R
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
10 Amino Acid Structure
Background image of page 10
11 Amino Acid Structure Structure [Table 6.1] 1) Aliphatic side chains –straight or branched chains 1) Side chains with OH groups –readily modified with phosphate groups, etc. 1) Side chains with sulfur atoms 2) Side chains with acidic groups or their amides 3) Side chains with basic groups 4) Side chains with aromatic rings 5) Imino acid 6) Amino acids formed posttranslationally
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
12 Amino Acid Charge Amino acids are ionized in aqueous solutions Net electrical charge determined by side chain Neutral-switterion Negatively charged-dicarboxylic acid (aspartate glutamate) Positively charged-dibasic (lysine, histidine and arginine) H 3 N + -CH-COO- | R
Background image of page 12
Image of page 13
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 56

09082011FNTR342-ProtDigest - Digestion, Absorption, and...

This preview shows document pages 1 - 13. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online