09:22:2011 - Vitamin A - Vitamin A Discovery Elmer Verner...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Vitamin A Discovery Elmer Verner McCollum The University of Wisconsin (1913) - one of the first to work with rats as an experimental model. he fed different diets then bred and weaned the pups to the different diets. Found: Diets with butter, egg yolks and cod-liver oil = healthy rats Diets with olive oil, lard or almond oil = rats with sore eyes, infections, such as pneumonia The researchers found a substance in the butter, egg and cod-liver oil that was lacking in the vegetable fats. This was vitamin A, the first vitamin to be discovered, but it was not called vitamin A. McCollum called it fat-soluble factor A . This was seen as great news by Wisconsin farmers as well as farmers around the country due to increased use of margarine. Margarine was made from cheaper fats but lacked vitamin A. Margarine is fortified with Vitamin A. McCollum was recruited by Johns Hopkins in 1917. He was brought in to promote the study of nutrition. Not taken seriously by physicians. continued his experiments with rats and diet. also felt the pubic needed to be told about nutrition. nutrition editor for McCall's and wrote over 160 articles designed to guide the American housewife in feeding her family. promoted the idea that a variety of foods needed to be in the diet. McCollum and his group knew that there were Vitamin A substances in plants, it was not until 1930s that scientists were able to show that the body could convert carotenoids into active vitamin A. Alfred Sommers work in Indonesia from 1976-1980 demonstrated the direct link between Vitamin A and general infection and the immune system was clarified. Able to clearly demonstrate the effect on Vitamin A deficiency on the immune system occurred before the development of the eye problems. There had been opportunities to see this all along but the medical community did not grasp it Sources otenoids : plant origin most common that show provitamin A activity: -carotene*, -carotene, -cryptoxanthin, lycopene, lutein, and zeaxanthin. This translates to: deeply colored fruits and vegetables. -carotene: carrots , broccoli , cantaloupe , squash , peas, spinach, sweet pot -cryptoxanthin: fruits lycopenes: tomatoes and watermelon zeaxanthin: orange peppers, corn, potatoes and eggs lutein: broccoli , beets, kiwi, fruit, eggs....
View Full Document

This note was uploaded on 11/25/2011 for the course NTR 365 taught by Professor Sweltzer during the Fall '11 term at University of Texas at Austin.

Page1 / 21

09:22:2011 - Vitamin A - Vitamin A Discovery Elmer Verner...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online