{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

10:06:2011 - Vitamin D - Vitamin D Discovery Rickets...

Info icon This preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Vitamin D Discovery - Rickets Documentation of rickets as early as 1650 by physicians in England. • Disease was associated with children in cities found in northern latitudes, children were described as having “soft bones.” • Blamed on array of causes: poor sanitation, lack of exercise, dirty clothes and syphyllis • In the 1800’s a French physician, Armand Trousseau, was able to connect rickets in children with osteomalacia in adults. Also identified cold and sunless climates and poor diet as causes. Used cod-liver oil, prolonged breast feeding if mother’s milk as good and sun exposure for treatment. Eighteenth century – industrial revolution led to ↑ in rickets. 1) burning coal – smog 2) ↑factory work 3) ↑child labor
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Discovery continued Initial studies were with lion cubs in the London Zoo and puppies. lions recovered when fed bones, milk and cod-liver oil, puppies recovered when fed butterfat and cod-liver oil and exercise outside. Initially missed on the puppies – thought vitamin A in the diet and actual exercise were the cure. Orphanages in post WWI in Berlin offered opportunities to work with rickets. Huldschinsky used a sun lamp (provided UV rays) to cure rickets in babies. • Harriette Chick used controlled diet studies of orphans and found: 1) Toddlers were prone to development. 2) Sunshine and cod-liver oil prevented and cured. 3) Huldschinsky’s mercury vapor lamp cured rickets. 4) Rickets was worse in the winter.
Image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern