11:10:11 - Selenium and Iodine 2011

11:10:11 - Selenium and Iodine 2011 - Selenium Chemistry is...

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Unformatted text preview: Selenium Chemistry is similar to sulfur. Can substitute for sulfur. Sources Variable – based on soil composition. Plants : cereals and grains range 10 μg/100g - >80 μg/100g Animal: meats (esp. organ) range 40 μg/100g – 150 μg/100g Dairy: about 30 μg/100g Mercury content can affect bioavailability in fish: binds with selenium. DRI μg/day 1 – 3 20 4 – 8 30 Males 9 – 13 40 14 - >70 55 Females 9 – 13 40 14 - >70 55 Fig. 12-14, p. 507 Plant form Animal source Absorption Organic form (found in food): selenomethionine, selenocysteine Inorganic forms (some vegetables, yeast, and supplements): selenite, selenate, seleni Duodenum is primary site but can also be absorbed from jejunum and ileum. The organic forms, selenomethionine and selenocysteine are absorbed via the amino acid transport systems. Selenium is transported as selenoamino acids of VLDLs, LDLs and other blood proteins. Fig. 12-15, p. 507 Storage Selenium is found in many organs and tissues. Highest: thyroid gland, kidney, liver, heart, pancreas, and muscle. Fig. 12-16, p. 508 Breaks down Form the body will use to make selenophosphate Functions Primary function: as part of selenium-dependent enzymes. Other functions exist but are poorly understood. Common selenium –dependent enzymes: Glutathione Peroxidase (GPX 1-4) – catalyzes removal of hydrogen peroxides and hydroperoxides. p. 509 Selenium dependent Active role as an antioxidant. Vitamin E, iron assist in the reaction. Functions Primary function: as part of selenium-dependent enzymes....
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This note was uploaded on 11/25/2011 for the course NTR 365 taught by Professor Sweltzer during the Fall '11 term at University of Texas.

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11:10:11 - Selenium and Iodine 2011 - Selenium Chemistry is...

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