Tutorial 8 assignment TA

Tutorial 8 assignment TA - Biology 2C03: Genetics Tutorial...

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Biology 2C03: Genetics Tutorial 11 Chromosome rearrangements 1. Explain the following observation by assuming that there is a Robertsonian translocation involved. In a family with two children, the daughter has 45 chromosomes, one less than the 46 of a typical human karyotype, but no symptoms of any disorders. The son, however, has 46 chromosomes and shows symptoms typical of Down's syndrome. How is this possible? (2 marks) The mother is a carrier for a 14-21 translocation (translocation carrier). The daughter is also a translocation carrier. The son has a translocated chromosome (14-21) and a normal chromosome 21 from the mother and a normal set of chromosomes from the father. 2. Two nonhomologous chromosomes have the following segments: (1 mark) A B C D E F G R S T U V W X Draw chromosomes that would result from the following chromosome rearrangements. a. reciprocal translocation of CD and TU b. reciprocal translocation of CD and W c. Robertsonian translocation a. A B T U E F G R
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Tutorial 8 assignment TA - Biology 2C03: Genetics Tutorial...

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