DIAG 2725 Midterm Notes - Malignant tumors of the skin...

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Malignant tumors of the skin Malignant melanoma MOST AGGRESSIVE Early blood spread Characteristics of suspicious changes of mole Change in color Increase in size Itching Bleeding Squamous cell carcinoma Less aggressive than melanoma Late blood spread Early lymphatic spread Basal cell carcinoma AKA Rodent ulcer LEAST AGGRESSIVE Locally malignant Common abnormalities of fingernails Splinter hemorrhage => subacute bacterial endocarditis (SBE) Koilonychia => AKA spoon nail => iron deficiency, anemia, or fungus infection Clubbing => chronic hypoxia => emphysema Strippling => psoriasis => pits Thyroid gland Hyperfunction => graves disease Hypofunction => myxdema or cretinism Pituitary gland Hyperfunction => acromegally (after puberty) or gigantism (before puberty Adrenal gland Hyperfunction => cushing’s disease Hypofunction => addison’s disease Pulmonary hypertension Mitral stenosis Increased BP of over 30 mm Hg Caused by left side heart failure, COPD, fibrotic lung diseases, or pulmonary embolism or thrombus Cor pulmonale Right ventricular hypertrophy Due to pulmonary pathology Chronic condition Involves right side heart failure Asthma COPD Characterized by airway inflammation Result from airway hyperactivity Triggered by allergens, anxiety, upper respiratory infections, cigarettes 3 things that happen Muscle spasm Excess mucous production Congestion of lumen
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Subacute bacterial endocarditis (SBE) Inflammation of endocardium around valve or scar tissue Requires 2 factors Presence of valvular lesions or scar of previous heart surgery Bacterium of streptococci viridans (80% of cases) Normal bacterial flora of oral cavity Infection occurs after dental work Fallot’s tetrology
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