RADD 2711 Lecture 4 Summer 2011

RADD 2711 Lecture 4 Summer 2011 - METABOLIC DISORDERS...

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METABOLIC DISORDERS
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OSTEOPOROSIS *Most common* metabolic disease of bone “Osteoporosis” = increased porosity of bone, porous bone
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Normal Thinning Osteoporosis
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OSTEOPOROSIS Resorption of the supporting trabeculae Spares the vertically oriented stress trabeculae Pseudo-hemagiomatous appearance
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OSTEOPORO SIS
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OSTEOPOROSIS in bone QUANTITY Normal bone QUALITY
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OSTEOPENIA “OSTEOPENIA Term used to describe general radiolucent bone “Poverty of bone” Descriptive term Not a cause
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OSTEOPOROSIS 3 Types of Osteoporosis: 1. Generalized Osteoporosis 2. Regionalized Osteoporosis 3. Localized Osteoporosis
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1. Generalized Osteoporosis
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CONDITIONS ASSOCIATED WITH GENERALIZED OSTEOPOROSIS Malignant bone disease Senile and postmenopausal Acromegaly Alcoholism Hemolytic anemia Heparin therapy (anticoagulant) Hyperparathyroidism Steroids
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OSTEOPOROSIS 1. GENERALIZED OSTEOPOROSIS bone density in skeleton Especially: axial skeleton pelvis proximal long bones
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OSTEOPOROSIS 1. GENERALIZED OSTEOPOROSIS Most commonly due to : A) Postmenopausal females B) Aging 2° to… hormones, Ca++ intake, activity level, diet, osteoblastic activity
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OSTEOPOROSIS Bone loss – begins at 35yoa hormones Stimulates osteoclastic activity
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RADD 2711 Lecture 4 Summer 2011 - METABOLIC DISORDERS...

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